The term fuzzy logic is used in this paper to describe an imprecise logical system, FL, in which the truth-values are fuzzy subsets of the unit interval with linguistic labels such as true, false, not true, very true, quite true, not very true and not very false, etc. The truth-value set, , of FL is assumed to be generated by a context-free grammar, with a semantic rule providing a means of computing the meaning of each linguistic truth-value in as a (...) fuzzy subset of [0, 1].Since is not closed under the operations of negation, conjunction, disjunction and implication, the result of an operation on truth-values in requires, in general, a linguistic approximation by a truth-value in . As a consequence, the truth tables and the rules of inference in fuzzy logic are (i) inexact and (ii) dependent on the meaning associated with the primary truth-value true as well as the modifiers very, quite, more or less, etc. (shrink)

Background: Clinical genomic implementation studies pose challenges for informed consent. Consent forms often include complex language and concepts, which can be a barrier to diverse enrollment, and these studies often blur traditional research-clinical boundaries. There is a move toward self-directed, web-based research enrollment, but more evidence is needed about how these enrollment approaches work in practice. In this study, we developed and evaluated a literacy-focused, web-based consent approach to support enrollment of diverse participants in an ongoing clinical genomic implementation study. (...) Methods: As part of the Cancer Health Assessments Reaching Many (CHARM) study, we developed a web-based consent approach that featured plain language, multimedia, and separate descriptions of clinical care and research activities. CHARM offered clinical exome sequencing to individuals at high risk of hereditary cancer. We interviewed CHARM participants about their reactions to the consent approach. We audio recorded, transcribed, and coded interviews using a deductively and inductively derived codebook. We reviewed coded excerpts as a team to identify overarching themes. Results: We conducted 32 interviews, including 12 (38%) in Spanish. Most (69%) enrolled without assistance from study staff, usually on a mobile phone. Those who completed enrollment in one day spent an average of 12 minutes on the consent portion. Interviewees found the information simple to read but comprehensive, were neutral to positive about the multimedia support, and identified increased access to testing in the study as the key difference from clinical care. Conclusions: This study showed that interviewees found our literacy-focused, web-based consent approach acceptable; did not distinguish the consent materials from other online study processes; and valued getting access to testing in the study. Overall, conducting empirical bioethics research in an ongoing clinical trial was useful to demonstrate the acceptability of our novel consent approach but posed practical challenges. (shrink)

I explore some of the ways that assumptions about the nature of substance shape metaphysical debates about the structure of Reality. Assumptions about the priority of substance play a role in an argument for monism, are embedded in certain pluralist metaphysical treatments of laws of nature, and are central to discussions of substantivalism and relationalism. I will then argue that we should reject such assumptions and collapse the categorical distinction between substance and property.

Quentin Smith has argued that the new tenseless theory of time is faced with insurmountable problems and should be abandoned in favour of the tensed theory of time. Smith;s main argument attacks the fundamental premise of the tenseless theory: that tenseless truth conditions for tokens of tensed sentences adequately capture the meaning of tensed sentences. His position is that tenseless truth conditions cannot explain the logical relations between tensed sentences, thus the tensed theory must be accepted. Against Smith, this paper (...) adopts an alternative approach to the explanation of the entailment relations between sentences which contain indexicals. The approach drops the reliance upon tokens and instead relies on the evaluation of sentence types with respect to a context rather than upon actual or possible utterances of tokens of the types. This (new) version of the tenseless theory of time can adequately explain the relevant entailment relations between tensed sentences. (shrink)

Moral Case Deliberations are reflective dialogues with a group of participants on their own moral dilemmas. Although MCD is successful as clinical ethics support, it also has limitations. 1. Lessons learned from individual MCDs are not shared in order to be used in other contexts 2. Moral learning stays limited to the participants of the MCD; 3. MCD requires quite some organisational effort, 4. MCD deals with one individual concrete case. It does not address other, similar cases. These limitations warrant (...) research into complementary ways of providing CES to healthcare professionals. Our research objective was therefore to develop a low threshold CES tool based on a series of MCDs on autonomy in long-term care. We used a qualitative research design in which we analyzed the process and content of a series of MCDs, combined with reflections on the theoretical background of MCD. In total 28 MCDs were analyzed by means of a thematic content analysis. In various rounds of development, the results of the analysis were combined with theoretical reflections on CES. Consequently, the tool was evaluated in three focus groups and adjusted. The CES tool, called ‘moral compass’, guides the users through a series of six subsequent questions in order to methodically reflect on their concrete moral dilemma, in the form of a booklet of 23 pages. It combines a methodical element that encourages and structures a reflection process with a substantive element, including norms, values, options, strategies, and insights regarding dealing with client autonomy. By using data from a series of MCDs, combined with theoretical reflections on MCD, ethics support and moral learning, we developed a thematic, low-threshold CES tool that supports healthcare professionals in daily practice in dealing with moral questions regarding client autonomy. It integrates examples and insights from earlier MCDs on the same topic. The moral compass is not a replacement of, but can be used complementary to MCD. The feasibility and impact of the moral compass need to be investigated in an evaluative follow-up study. The methodology presented in this paper may be used to develop moral compasses on different topics in various healthcare organizations. (shrink)

The sports world has historically rejected the practice of tanking. I argue that this attitude is unwarranted. To do so, I introduce a concept called strategic suboptimal play (SSP), which is the practice of incurring the risk of a short-term competitive disadvantage to increase the chances of gaining a longer-term competitive advantage. Tanking is just an instance of SSP employed in higher-order games, i.e. games that are at least partially played by other games, like tournaments or seasons. Since SSP is (...) integral to every sport, there are currently no easy grounds for rejecting it outright. As such, the same is true of tanking. I will explore some possible reasons why tanking is wrongly thought objectionable, as well as some objections to and implications of my argument for competitive sports more broadly. (shrink)

In response to counterexamples involving late preemption, David Lewis (1986) revised his original (1973) counterfactual analysis of causation to include the notion of quasi-dependence. Jonardon Ganeri, Paul Noordhof and Murali Ramachandran (1998) argue that their ‘PCA*-analysis’ of causation solves the problem of late preemption and is superior to Lewis’s analysis. I show that neither quasi-dependence nor the PCA*-analysis solves the problem of late preemption.

This study is based on the 1983 Rural Health Survey of Ethiopia. Patterns and levels of child morbidity by age, sex, geographic region, and sanitary facilities are examined. Morbidity levels peak in the second year of life. Diarrhoeal diseases are of major importance, especially among infants and toddlers. Parasitic diseases, and respiratory diseases other than pneumonia, become increasingly important with age.There are no significant sex differentials in morbidity except for higher rates of diarrhoeal diseases among female children. Geographic differentials are (...) quite marked with particularly high morbidity levels from all disease types in the western mountainous regions of Ethiopia. Access to high quality drinking water, a latrine, and garbage disposal, are strongly related to reduced overall morbidity levels, though not necessarily to reduced diarrhoeal disease levels. (shrink)

A leaf falls to the ground, wafting lazily on the afternoon breeze. Clouds move across the sky, and birds sing. Are these events governed by universal laws of nature, laws that apply everywhere without exception, subsuming events such as the falling of the leaf, the movement of the clouds and the singing of the birds? Are such laws part of a small set of fundamental laws, or descended from such a set, which govern everything there is in the world?

A considerable number of workers interviewed have stated their belief that Jews have too much power. The notion of power in this context has a wide range. It covers the most diversified phenomena—from holding minor positions in administration or business to dominating everything and wielding unchecked power over the world. The idea of Jewish power as it fascinates our interviewees is vague and hazy. To establish its real contents, it seems advisable to discuss these statements first that refer to the (...) widest and most comprehensive concept of universal Jewish domination. In statements made by our interviewees, references to Jews as.. (shrink)

I claim that Mill has a theory of poetry which he uses to reconcile nineteenth century associationist psychology, the tendency of the intellect to dissolve associations, and the need for educated members of society to desire utilitarian ends. The heart of the argument is that Mill thinks reading poetry encourages us to feel the feelings of others, and thus to develop pleasurable associations with the pleasurable feelings of others and painful associations with the painful feelings of others. Once the associations (...) are developed, they are supported and maintained by our natural capacity for sympathy and by external elements in society, and provide motivation for the pursuit of utilitarian ends. Further, the additional support causes the associations to be strengthened to the extent that they come to be seen as ‘natural and necessary’, and as such are immune from the dissolving force of the intellect. (shrink)

If an object has a property essentially, it has that property in every possible world according to which it exists.2 If an object has a property accidentally, it does not have that property in every possible world according to which it exists. Claims about an object’s essential or accidental properties are de re modal claims, and essential and accidental properties are de re modal properties. Take an object’s modal profile to specify its essential properties and the range of its accidental (...) properties. Note that “world” as I am using it is a term of art: a modal realist believes that there are many concrete worlds, while the actualist believes in only one concrete world, the actual world. The ersatzist is an actualist who takes nonactual possible worlds and their contents to be abstracta. Essentialism is the view that objects have properties essentially, but one should distinguish deep essentialism from shallow essentialism. Deep essentialists take the (nontrivial) essential properties of an object to determine its nature— such properties give sense to the idea that an object has a unique and distinctive character, and make it the case that an object has to be a certain way in order for it to be at all.3 As Stephen Yablo (1987, 297) describes it, the essence of a thing is “an assortment of properties in virtue of which it is the entity in question,” as well as “a measure of what is required for it to be that thing.” Intuitively, on the deep essentialist picture, an ordinary object has essential properties, and it must have its essential properties in order for it to exist. On this view, objects’ essential properties are absolute, i.e., are not determined by contexts of describing (or thinking, etc.) about the object, and truths about such properties are absolute truths.4 Shallow essentialists oppose deep essentialists: they reject the view that objects can be said to have essential properties independently of contexts of description or evaluation, and so substitute context-dependent truths for the deep essentialist’s context-independent ones.. (shrink)

In the 21stcentury, there is a turn of thinking toward its reorientation first of all to the human as an author of thought and not to the nature, existing independently of us and of the process of scientific knowledge obtaining. It is possible to see the difference of these two types of thinking in the context of dialogue between W. Whewell’s philosophy and the scientific investigations after the scientific revolution in the beginning of the 20thcentury. In the philosophy of 21stcentury, (...) man is a social being and this is the basis of social philosophy. The artificial world around us is created by a human, it has its foundation in the laws of thinking but not the laws of nature. The foundations of both systems are quite different. In what way can we achieve mutual understanding between them? From both sides some aspects can be put forward, for instance, the concept of a mediator of a thought. This concept is studied actively by W. Whewell and by philosophers of our time, and this leads in both cases to some unexpected interpretation of the basic question of philosophy: the border between thing and thought is becoming less noticeable. We can come to the same result, going by different ways. Whewell finds common qualities for some group of things. Social philosophers are interested in what makes things different. Not one of these idealizations corresponds completely to the reality. Always something is not taken into consideration. A thinker chooses out of real world some of its characteristics that become a basis of a thought system, which explains everything but in its own way. The paper demonstrates the way of possible creation of a new type of thinking. (shrink)

As you face a life-defining change, you might ask yourself: Who will I become? This can be understood as a question about the nature and character of your future life, asked from your first person, or subjective, perspective. The nature and character of your conscious, first person, lived experience is a defining constituent of what it is like to be you. Framed this way, knowing the nature of your future lived experience is a way of knowing your future self. In (...) this paper, I explore this way of understanding one’s self and its implications for understanding life-defining changes in high-stakes contexts. My exploration of this way of understanding one’s self highlights the role of experience in grasping perceptual truths, and the importance of imagination, empathy, and testimony in self-understanding and prediction. (shrink)